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Hisafumi Yamada-Okabe Selected Research

parathyroid hormone-related protein (1-34)

11/2005Humanized monoclonal antibody against parathyroid hormone-related protein suppresses osteolytic bone metastasis of human breast cancer cells derived from MDA-MB-231.
9/2004Generation of a humanized monoclonal antibody against human parathyroid hormone-related protein and its efficacy against humoral hypercalcemia of malignancy.

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Hisafumi Yamada-Okabe Research Topics

Disease

24Neoplasms (Cancer)
02/2018 - 09/2003
13Hepatocellular Carcinoma (Hepatoma)
11/2010 - 07/2002
7Multiple Myeloma
01/2013 - 04/2005
6Carcinoma (Carcinomatosis)
05/2015 - 05/2004
5Adenocarcinoma of Lung
02/2018 - 08/2010
5Breast Neoplasms (Breast Cancer)
03/2010 - 08/2005
4Lung Neoplasms (Lung Cancer)
02/2018 - 09/2004
3Hypoxia (Hypoxemia)
06/2011 - 05/2003
3Melanoma (Melanoma, Malignant)
05/2011 - 05/2007
3Humoral Hypercalcemia Of Malignancy
01/2007 - 09/2004
2Fibrosis (Cirrhosis)
01/2023 - 09/2003
2Endometriosis
01/2023 - 09/2003
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2011 - 05/2007
2Hypercalcemia (Milk Alkali Syndrome)
05/2011 - 09/2005
2Anorexia
05/2011 - 01/2007
2Body Weight (Weight, Body)
05/2011 - 09/2005
2Renal Cell Carcinoma (Grawitz Tumor)
12/2008 - 02/2005
2Neoplasm Metastasis (Metastasis)
09/2008 - 11/2005
2Leukemia
05/2007 - 09/2005
2Infections
07/2006 - 02/2005
2Inflammation (Inflammations)
08/2005 - 09/2003
2Pancreatic Neoplasms (Pancreatic Cancer)
09/2004 - 05/2004
1Disease Progression
01/2023
1Glioma (Gliomas)
06/2011
1Cachexia
05/2011
1Arthritis (Polyarthritis)
05/2011
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2010
1Mouth Neoplasms (Oral Cancer)
02/2010
1Squamous Cell Carcinoma of Head and Neck
02/2010
1Diarrhea
01/2010

Drug/Important Bio-Agent (IBA)

11Monoclonal AntibodiesIBA
04/2014 - 09/2004
8Parathyroid Hormone-Related ProteinIBA
05/2011 - 09/2004
8OligonucleotidesIBA
02/2005 - 07/2002
7Proteins (Proteins, Gene)FDA Link
05/2015 - 05/2003
4Messenger RNA (mRNA)IBA
06/2011 - 03/2003
4LC 6IBA
05/2011 - 09/2004
4DNA (Deoxyribonucleic Acid)IBA
09/2008 - 05/2004
3Interleukin-8 (Interleukin 8)IBA
01/2023 - 09/2003
3Tyrosine Kinase InhibitorsIBA
02/2018 - 10/2014
3Biomarkers (Surrogate Marker)IBA
05/2015 - 02/2005
3GlypicansIBA
11/2010 - 12/2008
3Estrogen ReceptorsIBA
03/2010 - 08/2005
3TamoxifenFDA LinkGeneric
03/2010 - 08/2005
3Fulvestrant (Faslodex)FDA Link
03/2010 - 08/2005
3Interleukin-6 (Interleukin 6)IBA
02/2010 - 09/2005
2Matrix Metalloproteinases (MMPs)IBA
02/2018 - 09/2003
2ErbB Receptors (EGF Receptor)IBA
02/2018 - 05/2015
2Complementary DNA (cDNA)IBA
06/2011 - 09/2003
2Immunoglobulin FragmentsIBA
06/2011 - 04/2005
2Peptides (Polypeptides)IBA
05/2011 - 01/2007
2LeptinIBA
05/2011 - 01/2007
2codrituzumabIBA
11/2010 - 12/2008
2Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
11/2010 - 01/2009
2Bone Marrow Stromal Antigen 2IBA
10/2010 - 12/2008
2Estrogens (Estrogen)FDA Link
08/2010 - 03/2009
2CytokinesIBA
08/2010 - 09/2005
2Capecitabine (Xeloda)FDA Link
01/2010 - 09/2003
2CH 4893237IBA
03/2009 - 08/2005
2AntigensIBA
12/2008 - 02/2006
2Antineoplastic Agents (Antineoplastics)IBA
12/2008 - 05/2004
2parathyroid hormone-related protein (1-34)IBA
11/2005 - 09/2004
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
09/2005 - 01/2004
2Hormones (Hormone)IBA
08/2005 - 07/2005
2CalciumIBA
06/2005 - 09/2004
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2023
1TOR Serine-Threonine KinasesIBA
02/2018
1Epidermal Growth Factor (EGF)IBA
02/2018
1Sirolimus (Rapamycin)FDA Link
02/2018
1Erlotinib Hydrochloride (CP 358,774)FDA Link
10/2014
1Gefitinib (Iressa)FDA Link
10/2014
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
04/2014
1DisulfidesIBA
06/2011
1Endo180IBA
06/2011
1Urokinase Plasminogen Activator ReceptorsIBA
06/2011
1Small Interfering RNA (siRNA)IBA
06/2011
1hydroxide ionIBA
05/2011
1Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
11/2010
1Aromatase (CYP19)IBA
08/2010
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
08/2010
1CH 4986399IBA
03/2010
1Selective Estrogen Receptor Modulators (SERM)IBA
03/2010
1Conditioned Culture MediaIBA
02/2010
1Irinotecan (Camptosar)FDA LinkGeneric
01/2010
1Cholinergic Agents (Cholinergics)IBA
01/2010
1Bevacizumab (Avastin)FDA Link
01/2010
1Cisplatin (Platino)FDA LinkGeneric
01/2010
1CamptothecinIBA
01/2010
1Cetuximab (Erbitux)FDA Link
01/2010
1ProdrugsIBA
01/2010
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2010
1Aromatase InhibitorsIBA
03/2009
1AntibodiesIBA
01/2009
1CarbohydratesIBA
12/2008
1InterferonsIBA
12/2008

Therapy/Procedure

7Therapeutics
01/2023 - 04/2005
2Ligation
06/2011 - 05/2007
2Lasers (Laser)
08/2010 - 05/2004
2Hepatectomy
02/2008 - 06/2005
1Subcutaneous Injections
01/2023
1Oral Administration
05/2011